Understanding risk in hypercholesterolemia
نویسندگان
چکیده
منابع مشابه
Risk of brain infarction in familial hypercholesterolemia.
We followed 54 subjects with heterozygous familial hypercholesterolemia for an average of 10 (range 3-14) years. Half were treated surgically with partial ileal bypass and the other half (matched for age, sex, coronary heart disease, blood pressure, diabetes mellitus, smoking, obesity, and serum cholesterol concentration) were treated conservatively with diet and hypolipidemic drugs. The mean d...
متن کاملObesity and risk of hypercholesterolemia in Iranian northern adults
BACKGROUND The main aim of this study was to evaluate the association between serum cholesterol level and body mass index (BMI) in northern Iran. METHODS This was a cross-sectional study carried out on the 1995 subjects (997 males and 998 females) aged 25-65 years that were selected using multistage cluster sampling method. Plasma cholesterol was measured in the morning after a 12-hour fastin...
متن کاملRisk of Fatal Stroke in Patients With Treated Familial Hypercholesterolemia
Background and Purpose—Although it is recognized that in heterozygous familial hypercholesterolemia, large extracranial carotid vessels are affected by atherosclerosis, the risk of fatal stroke after treatment with cholesterollowering therapy remains uncertain. The goal of this study was to determine the risk of fatal stroke in patients with treated familial hypercholesterolemia. Methods—A coho...
متن کاملGenetic determinants of cardiovascular disease risk in familial hypercholesterolemia.
OBJECTIVE To investigate the contribution of polymorphisms in multiple candidate genes to cardiovascular disease (CVD) risk in a large cohort of patients with heterozygous familial hypercholesterolemia (FH). METHODS AND RESULTS We genotyped 1940 FH patients for 65 polymorphisms in 36 candidate genes. During 91.451 person-years, 643 (33.1%) patients had at least 1 cardiovascular event. Multifa...
متن کاملRisk of Fatal Stroke in Patients With Treated Familial Hypercholesterolemia
Background and Purpose—Although it is recognized that in heterozygous familial hypercholesterolemia, large extracranial carotid vessels are affected by atherosclerosis, the risk of fatal stroke after treatment with cholesterollowering therapy remains uncertain. The goal of this study was to determine the risk of fatal stroke in patients with treated familial hypercholesterolemia. Methods—A coho...
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ژورنال
عنوان ژورنال: Clinical Cardiology
سال: 2003
ISSN: 0160-9289,1932-8737
DOI: 10.1002/clc.4960261303